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Reactive oxygen species and cellularstress signaling. Biochem J

The nutrition side of breaking the inflammation loop involves removing the biggest drivers and adding anti-inflammatory support: Eliminate or sharply reduce processed vegetable oils (soybean, corn, canola) which promote inflammatory pathways Reduce added sugar and refined carbohydrates that spike insulin and trigger inflammatory responses Add omega-3 rich foods (wild salmon, sardines, mackerel) or high-quality fish oil Include turmeric, ginger, and dark leafy greens regularly Identify and remove personal food sensitivities through elimination or testing When the dietary inflammation load goes down and the anti-inflammatory peptides go to work, patients often notice a shift within weeks

Dietary sources of Vitamin B12 include animal products like meat, poultry, fish, dairy, and oral supplements

References: Johnson, Donovan B., and Matthew Varacallo

Moll S, Varga EA